Owen S. Good, writing for Polygon:
An iOS version of The Binding of Isaac: Rebirth was rejected by Apple on grounds it depicts violence toward children, the game's publisher said Saturday evening.
Tyrone Rodriguez, the founder of Nicalis and a producer and developer for the game, tweeted this image of Apple's rejection notice, which notes that "Your app contains content or features that depict violence towards, or abuse of, children, which is not allowed on the App."
You know your App Review has a problem when even Nintendo has accepted the same game a year ago. This wouldn't be the first time Apple's App Review team has shown less respect for mature themes expressed through videogames (the same themes being generally okay for other types of entertainment) and I hope this rejection gets reversed. The Binding of Isaac is a fantastic game and Apple should be thrilled to have these kinds of indie titles on the App Store.