After the release of iOS 5 last year, several users complained that the Newsstand app (effectively a "folder" for magazine and newspaper subscriptions) couldn't be hidden from the Springboard. Because of its nature of glorified folder, users couldn't even put it away in an existing folder on the Home screen. However, people soon figured out a trick to make the Springboard hide Newsstand.
This year, well-known Cydia developer Filippo Bigarella has released a simple Mac app to hide Newsstand from any iOS device with a single click. I've just tested the app personally on my iPhone 5 running iOS 6, and it works as advertised. Even better, the app doesn't require a jailbreak at all, as it leverages the existing "folder trick", albeit making it easier to access.
Simply download StifleStand, and open it on your Mac. Make sure a device is plugged in and recognized by the app. Hit the Hide Newsstand button, and watch as Newsstand gets put into a folder called "Magic" on your Home screen. It literally takes one second to complete.
Please note: Just like on iOS 5 last year, opening Newsstand from a folder will crash Springboard. Use this tweak only if you don't use Newsstand.
You can then rename the folder and put more apps into it. One bug I've noticed is that, because Newsstand isn't meant to be put into a folder, if the folder is closed you won't see the smaller preview icon for Newsstand. You can avoid this by placing more apps into the folder, leaving Newsstand at the end, so you won't see the empty spot from your Home screen.